Recombinant Human GRHPR Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GRHPR-2502H
• Product Overview: GRHPR MS Standard C13 and N15-labeled recombinant protein (NP_036335) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.7 kDa
• AA Sequence: MRPVRLMKVFVTRRIPAEGRVALAR AADCEVEQWDSDEPIPAKELERGVA GAHGLLCLLSDHVDKRILDAAGANL KVISTMSVGIDHLALDEIKKRGIRV GYTPDVLTDTTAELAVSLLLTTCRR LPEAIEEVKNGGWTSWKPLWLCGYG LTQSTVGIIGLGRIGQAIARRLKPF GVQRFLYTGRQPRPEEAAEFQAEFV STPELAAQSDFIVVACSLTPATEGL CNKDFFQKMKETAVFINISRGDVVN QDDLYQALASGKIAAAGLDVTSPEP LPTNHPLLTLKNCVILPHIGSATHR TRNTMSLLAANNLLAGLRGEPMPSE LKLTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GRHPR glyoxylate reductase/hydroxypyruvate reductase [ Homo sapiens (human) ]
• Official Symbol: GRHPR
• Synonyms: GRHPR; glyoxylate reductase/hydroxypyruvate reductase; GLXR; PH2; primary hyperoxaluria type 2; glycerate-2-dehydrogenase; GLYD
• Gene ID: 9380
• mRNA Refseq: NM_012203
• Protein Refseq: NP_036335
• MIM: 604296
• UniProt ID: Q9UBQ7