Recombinant Human GSC2 Protein, GST-tagged

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Recombinant Human GSC2 Protein, GST-tagged

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Cat.No. : GSC2-5389H
Product Overview : Human GSC2 full-length ORF ( NP_005306.1, 1 a.a. - 205 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 48.95 kDa
AA Sequence : MAAAAGGAAS RRGAGRPCPF SIEHILSSLP ERSLPARAAC PPQPAGRQSP AKPEEPGAPE AAPCACCCCC GPRAAPCGPP EAAAGLGARL AWPLRLGPAV PLSLGAPAGG SGALPGAVGP GSQRRTRRHR TIFSEEQLQA LEALFVQNQY PDVSTRERLA GRIRLREERV EVWFKNRRAK WRHQKRASAS ARLLPGVKKS PKGSC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GSC2 goosecoid homeobox 2 [ Homo sapiens ]
Official Symbol : GSC2
Synonyms : GSC2; goosecoid homeobox 2; goosecoid like, GSCL; homeobox protein goosecoid-2; GSC-2; GSC-L; GSCL;
Gene ID : 2928
mRNA Refseq : NM_005315
Protein Refseq : NP_005306
MIM : 601845
UniProt ID : O15499

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