Recombinant Human GSDMB Protein, GST-tagged

• Cat.No.: GSDMB-4391H
• Product Overview: Human GSDML full-length ORF ( AAH25682, 1 a.a. - 411 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 70.95 kDa
• AA Sequence: MFSVFEEITRIVVKEMDAGGDMIAV RSLVDADRFRCFHLVGEKRTFFGCR HYTTGLTLMDILDTDGDKWLDELDS GLQGQKAEFQILDNVDSTGELIVRL PKEITISGSFQGFHHQKIKISENRI SQQYLATLENRKLKRELPFSFRSIN TRENLYLVTETLETVKEETLKSDRQ YKFWSQISQGHLSYKHKGQREVTIP PNRVLSYRVKQLVFPNKETMSAGLD IHFRGKTKSFPEGKSLGSEDSRNMK EKLEDMESVLKDLTEEKRKDVLNSL AKCLGKEDIRQDLEQRVSEVLISRE LHMEDSDKPLLSSLFNAAGVLVEAR AKAILDFLDALLELSEEQQFVAEAL EKGTLPLLKDQVKSVMEQNWDELAS SPPDMDYDPEARILCALYVVVSILL ELAEGPTSVSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GSDMB gasdermin B [ Homo sapiens ]
• Official Symbol: GSDMB
• Synonyms: GSDMB; gasdermin B; gasdermin like , GSDML; gasdermin-B; PRO2521; gasdermin-like protein; GSDML; PP4052
• Gene ID: 55876
• mRNA Refseq: NM_001042471
• Protein Refseq: NP_001035936
• MIM: 611221
• UniProt ID: Q8TAX9