Recombinant Human GSDMD protein, GST-tagged

• Cat.No.: GSDMD-32H
• Product Overview: Recombinant Human GSDMD(1 a.a. - 484 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 78.98 kDa
• AA Sequence: MGSAFERVVRRVVQELDHGGEFIPV TSLQSSTGFQPYCLVVRKPSSSWFW KPRYKCVNLSIKDILEPDAAEPDVQ RGRSFHFYDAMDGQIQGSVELAAPG QAKIAGGAAVSDSSSTSMNVYSLSV DPNTWQTLLHERHLRQPEHKVLQQL RSRGDNVYVVTEVLQTQKEVEVTRT HKREGSGRFSLPGATCLQGEGQGHL SQKKTVTIPSGSTLAFRVAQLVIDS DLDVLLFPDKKQRTFQPPATGHKRS TSEGAWPQLPSGLSMMRCLHNFLTD GVPAEGAFTEDFQGLRAEVETISKE LELLDRELCQLLLEGLEGVLRDQLA LRALEEALEQGQSLGPVEPLDGPAG AVLECLVLSSGMLVPELAIPVVYLL GALTMLSETQHKLLAEALESQTLLG PLELVGSLLEQSAPWQERSTMSLPP GLLGNSWGEGAPAWVLLDECGLELG EDTPHVCWEPQAQGRMCALYASLAL LSGLSQEPH
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: GSDMD gasdermin D [ Homo sapiens ]
• Official Symbol: GSDMD
• Synonyms: GSDMD; gasdermin D; gasdermin domain containing 1 , GSDMDC1; gasdermin-D; DF5L; FLJ12150; gasdermin domain containing 1; gasdermin domain-containing protein 1; DFNA5L; FKSG10; GSDMDC1
• Gene ID: 79792
• mRNA Refseq: NM_001166237
• Protein Refseq: NP_001159709
• UniProt ID: P57764
• Chromosome Location: 8q24.3