Recombinant Human GSS Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GSS Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GSS-3695H
Product Overview : GSS MS Standard C13 and N15-labeled recombinant protein (NP_000169) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 52.4 kDa
AA Sequence : MATNWGSLLQ DKQQLEELAR QAVDRALAEG VLLRTSQEPT SSEVVSYAPF TLFPSLVPSA LLEQAYAVQM DFNLLVDAVS QNAAFLEQTL SSTIKQDDFT ARLFDIHKQV LKEGIAQTVF LGLNRSDYMF QRSADGSPAL KQIEINTISA SFGGLASRTP AVHRHVLSVL SKTKEAGKIL SNNPSKGLAL GIAKAWELYG SPNALVLLIA QEKERNIFDQ RAIENELLAR NIHVIRRTFE DISEKGSLDQ DRRLFVDGQE IAVVYFRDGY MPRQYSLQNW EARLLLERSH AAKCPDIATQ LAGTKKVQQE LSRPGMLEML LPGQPEAVAR LRATFAGLYS LDVGEEGDQA IAEALAAPSR FVLKPQREGG GNNLYGEEMV QALKQLKDSE ERASYILMEK IEPEPFENCL LRPGSPARVV QCISELGIFG VYVRQEKTLV MNKHVGHLLR TKAIEHADGG VAAGVAVLDN PYPVTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GSS glutathione synthetase [ Homo sapiens (human) ]
Official Symbol : GSS
Synonyms : GSS; glutathione synthetase; GSH-S; GSH synthetase; glutathione synthase; GSHS; MGC14098;
Gene ID : 2937
mRNA Refseq : NM_000178
Protein Refseq : NP_000169
MIM : 601002
UniProt ID : P48637

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