Recombinant Human GTPBP3 Protein, GST-tagged

• Cat.No.: GTPBP3-4472H
• Product Overview: Human GTPBP3 full-length ORF (BAB55228.1, 1 a.a. - 492 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.4 kDa
• AA Sequence: MWRGLWTLAAQAARGPRRLCTRRSS GAPAPGSGATIFALSSGQGRCGIAV IRTSGPASGHALRILTAPRDLPLAR HASLRLLSDPRSGEPLDRALVLWFP GPQSFTGEDCVEFHVHGGPAVVSGV LQALGSVPGLRPAEAGEFTRRAFAN GKLNLTEVEGLADLIHAETEAQRRQ ALRQLDGELGHLCRGWAETLTKALA HVEAYIDFGEDDNLEEGVLEQADIE VRALQVALGAHLRDARRGQRLRSGA HVVVTGPPNAGKSSLVNLLSRKPVS IVSPEPGTTRDVLETPVDLAGFPVL LSDTAGLREGVGPVEQEGVRRARER LEQADLILAMLDASDLASPSSCNFL ATVVASVGAQSPSDSSQRLLLVLNK SDLLSPEGPGPGPDLPPHLLLSCLT GEGLDGLLEALRKELAAVCGDPSTD PPLLTRARHQHHLQGCLDALGHYKQ SKDLALAAEALRVARGHLTRLTGGG GTEEILDIIFQDFCVGK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GTPBP3 GTP binding protein 3 (mitochondrial) [ Homo sapiens ]
• Official Symbol: GTPBP3
• Synonyms: GTPBP3; GTP binding protein 3 (mitochondrial); tRNA modification GTPase GTPBP3, mitochondrial; FLJ14700; GTPBG3; MSS1; MTGP1; THDF1; mitochondrial GTP-binding protein 1; FLJ17836
• Gene ID: 84705
• mRNA Refseq: NM_001128855
• Protein Refseq: NP_001122327
• MIM: 608536
• UniProt ID: Q969Y2