Recombinant Human GUCY2D Protein, MYC/DDK-tagged

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Recombinant Human GUCY2D Protein, MYC/DDK-tagged

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Cat.No. : GUCY2D-2548H
Product Overview : Recombinant Human GUCY2D protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 119.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : GUCY2D guanylate cyclase 2D, membrane (retina-specific) [ Homo sapiens ]
Official Symbol : GUCY2D
Synonyms : CORD5; CORD6; CYGD; GUC1A4; GUC2D; LCA; LCA1; RCD2; retGC; RETGC-1; ROS-GC1; ROSGC
Gene ID : 3000
mRNA Refseq : NM_000180
Protein Refseq : NP_000171
MIM : 600179
UniProt ID : Q02846

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