Recombinant Human GYS2, His-tagged

• Cat.No.: GYS2-13635H
• Product Overview: Recombinant Human GYS2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-100a.a.
• Description: The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GYS2 glycogen synthase 2 (liver) [ Homo sapiens ]
• Official Symbol: GYS2
• Synonyms: GYS2; glycogen synthase 2 (liver); glycogen [starch] synthase, liver
• Gene ID: 2998
• mRNA Refseq: NM_021957
• Protein Refseq: NP_068776
• MIM: 138571
• UniProt ID: P54840
• Chromosome Location: 12p12.2-p11.2
• Pathway: Glucose metabolism, organism-specific biosystem; Glycogen Metabolism, organism-specific biosystem; Glycogen synthesis, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; Metabolism, organism-specific biosystem
• Function: glycogen (starch) synthase activity; glycogen (starch) synthase activity; protein homodimerization activity; transferase activity, transferring glycosyl groups