Recombinant Human HAP1 Protein, GST-tagged
Cat.No. : | HAP1-4573H |
Product Overview : | Human HAP1 full-length ORF ( AAI56729.1, 1 a.a. - 671 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Huntingtons disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 100.21 kDa |
AA Sequence : | MRPKRLGRCCAGSRLGPGDPAALTC APSPSASPAPEPSAQPQARGTGQRV GSRATSGSQFLSEARTGARPASEAG AKAGARRPSAFSAIQGDVRSMPDNS DAPWTRFVFQGPFGSRATGRGTGKA AGIWKTPAAYVGRRPGVSGPERAAF IRELEEALCPNLPPPVKKITQEDVK VMLYLLEELLPPVWESVTYGMVLQR ERDLNTAARIGQSLVKQNSVLMEEN SKLEALLGSAKEEILYLRHQVNLRD ELLQLYSDSDEEDEDEEEEEEEKEA EEEQEEEEAEEDLQCAHPCDAPKLI SQEALLHQHHCPQLEALQEKLRLLE EENHQLREEASQLDTLEDEEQMLIL ECVEQFSEASQQMAELSEVLVLRLE NYERQQQEVARLQAQVLKLQQRCRM YGAETEKLQKQLASEKEIQMQLQEE SVWVGSQLQDLREKYMDCGGMLIEM QEEVKTLRQQPPVSTGSATHYPYSV PLETLPGFQETLAEELRTSLRRMIS DPVYFMERNYEMPRGDTSSLRYDFR YSEDREQVRGFEAEEGLMLAADIMR GEDFTPAEEFVPQEELGAAKKVPAE EGVMEEAELVSEETEGWEEVELELD EATRMNVVTSALEASGLGPSHLDMN YVLQQLANWQDAHYRRQLRWKMLQK GECPHGALPAASRTSCRSSCR |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HAP1 huntingtin-associated protein 1 [ Homo sapiens ] |
Official Symbol : | HAP1 |
Synonyms : | HAP1; huntingtin-associated protein 1; HAP2; hHLP1; HIP5; HLP; neuroan 1; HAP-1; huntingtin-associated protein 2; |
Gene ID : | 9001 |
mRNA Refseq : | NM_001079870 |
Protein Refseq : | NP_001073339 |
MIM : | 600947 |
UniProt ID : | P54257 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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