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Recombinant Human HAP1 protein, His & GST-tagged

Cat.No. : HAP1-1598H
Product Overview : Recombinant Human HAP1 aa. (Pro160~Gln381 (Accession # P54257)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.9kDa
Protein length : Pro160~Gln381 (Accession # P54257)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 4.2
Gene Name : HAP1 huntingtin associated protein 1 [ Homo sapiens (human) ]
Official Symbol : HAP1
Synonyms : HAP1; huntingtin associated protein 1; HLP; HAP2; HIP5; hHLP1; huntingtin-associated protein 1; HAP-1; huntingtin-associated protein 2; neuroan 1
Gene ID : 9001
mRNA Refseq : NM_001079870.1
Protein Refseq : NP_001073339.1
UniProt ID : P54257

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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