Recombinant Human HDAC3 Protein, GST-tagged
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Cat.No. : | HDAC3-4643H |
Product Overview : | Human HDAC3 full-length ORF ( AAH00614, 1 a.a. - 428 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 72.82 kDa |
AA Sequence : | MAKTVAYFYD PDVGNFHYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP YQASQHDMCR FHSEDYIDFL QRVSPTNMQG FTKSLNAFNV GDDCPVFPGL FEFCSRYTGA SLQGATQLNN KICDIAINWA GGLHHAKKFE ASGFCYVNDI VIGILELLKY HPRVLYIDID IHHGDGVQEA FYLTDRVMTV SFHKYGNYFF PGTGDMYEVG AESGRYYCLN VPLRDGIDDQ SYKHLFQPVI NQVVDFYQPT CIVLQCGADS LGCDRLGCFN LSIRGHGECV EYVKSFNIPL LVLGGGGYTV RNVARCWTYE TSLLVEEAIS EELPYSEYFE YFAPDFTLHP DVSTRIENQN SRQYLDQIRQ TIFENLKMLN HAPSVQIHDV PADLLTYDRT DEADAEERGP EENYSRPEAP NEFYDGDHDN DKESDVEI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | HDAC3 histone deacetylase 3 [ Homo sapiens ] |
Official Symbol : | HDAC3 |
Synonyms : | HDAC3; histone deacetylase 3; HD3; RPD3; RPD3 2; SMAP45; RPD3-2; |
Gene ID : | 8841 |
mRNA Refseq : | NM_003883 |
Protein Refseq : | NP_003874 |
MIM : | 605166 |
UniProt ID : | O15379 |
◆ Recombinant Protein
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HDAC3-550H | Recombinant Human HDAC3 Protein (1-428 aa), His-SUMO-tagged | +Inquiry |
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HDAC3-11224Z | Recombinant Zebrafish HDAC3 | +Inquiry |
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◆ Lysates
HDAC3-572HCL | Recombinant Human HDAC3 cell lysate | +Inquiry |
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◆ Assay kits
Kit-1739 | HDAC3 Kinetic Assay Kit | +Inquiry |
Kit-2254 | HDAC3 Activity Fluorometric Assay Kit | +Inquiry |
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