Recombinant Human HDAC4 Protein, GST-tagged
Cat.No. : | HDAC4-4645H |
Product Overview : | Human HDAC4 full-length ORF ( AAH39904.1, 1 a.a. - 972 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 132.8 kDa |
AA Sequence : | MLAMKHQQELLEHQRKLERHRQEQE LEKQHREQKLQQLKNKEKGKESAVA STEVKMKLQEFVLNKKKALAHRNLN HCISSDPRYWYGKTQHSSLDQSSPP QSGVSTSYNHPVLGMYDAKDDFPLR KTASEPNLKLRSRLKQKVAERRSSP LLRRKDGPVVTALKKRPLDVTDSAC SSAPGSGPSSPNNSSGSVSAENGIA PAVPSIPAETSLAHRLVAREGSAAP LPLYTSPSLPNITLGLPATGPSAGT AGQQDAERLTLPALQQRLSLFPGTH LTPYLSTSPLERDGGAAHSPLLQHM VLLEQPPAQAPLVTDWYLSGLGALP LHAQSLVGADRVSPSIHKLRQHRPL GRTQSAPLPQNAQALQHLVIQQQHQ QFLEKHKQQFQQQQLQMNKIIPKPS EPARQPESHPEETEEELREHQALLD EPYLDRLPGQKEAHAQAGVQVKQEP IESDEEEAEPPREVEPGQRQPSEQE LLFRQQALLLEQQRIHQLRNYQASM EAAGIPVSFGGHRPLSRAQSSPASA TFPVSVQEPPTKPRFTTGLVYDTLM LKHQCTCGSSSSHPEHAGRIQSIWS RLQETGLRGKCECIRGRKATLEELQ TVHSEAHTLLYGTNPLNRQKLDSKK LLGSLASVFVRLPCGGVGVDSDTIW NEVHSAGAARLAVGCVVELVFKVAT GELKNGFAVVRPPGHHAEESTPMGF CYFNSVAVAAKLLQQRLSVSKILIV DWDVHHGNGTQQAFYSDPSVLYMSL HRYDDGNFFPGSGAPDEVGTGPGVG FNVNMAFTGGLDPPMGDAEYLAAFR TVVMPIASEFAPDVVLVSSGFDAVE GHPTPLGGYNLSARCFGYLTKQLMG LAGGRIVLALEGGHDLTAICDASEA CVSALLGNELDPLPEKVLQQRPNAN AVRSMEKVMEIHSKYWRCLQRTTST AGRSLIEAQTCENEEAETVTAMASL SVGVKPAEKRPDEEPMEEEPPL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HDAC4 histone deacetylase 4 [ Homo sapiens ] |
Official Symbol : | HDAC4 |
Synonyms : | HDAC4; histone deacetylase 4; HA6116; HD4; HDAC 4; HDAC A; HDACA; KIAA0288; histone deacetylase A; AHO3; BDMR; HDAC-4; HDAC-A; |
Gene ID : | 9759 |
mRNA Refseq : | NM_006037 |
Protein Refseq : | NP_006028 |
MIM : | 605314 |
UniProt ID : | P56524 |
Products Types
◆ Recombinant Protein | ||
HDAC4-1053H | Recombinant Human HDAC4 Protein, MYC/DDK-tagged | +Inquiry |
HDAC4-1054H | Recombinant Human HDAC4 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC4-1045H | Recombinant Human HDAC4 Protein (T648-T1057), His tagged | +Inquiry |
Hdac4-3369M | Recombinant Mouse Hdac4 Protein, Myc/DDK-tagged | +Inquiry |
HDAC4-1308H | Recombinant Human HDAC4 protein(Met612-Leu1084) | +Inquiry |
◆ Lysates | ||
HDAC4-001HCL | Recombinant Human HDAC4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1740 | HDAC4 Fluorogenic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHDAC4 affects cardiac hypertrophy and heart failure by regulating cardiac gene expression.
HDAC4 regulates immune responses and inflammation through gene expression control.
HDAC4 is important for neuronal development and linked to neurodegenerative diseases.
Stress and diet influence HDAC4 activity, affecting its role in gene regulation and cell processes.
Mutations in HDAC4 disrupt skeletal muscle development and contribute to muscular disorders.
HDAC4 controls gene expression by altering histone acetylation, affecting chromatin structure.
HDAC4 interacts with non-histone proteins, influencing various cellular functions.
Customer Reviews (3)
Write a reviewDependable protein-protein interaction assays; integral for our experiments.
Efficient protein purification services; consistent yield and purity.
Expertise in protein engineering; excellent service, highly recommended.
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