Recombinant Human HDAC7 Protein, GST-tagged

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Recombinant Human HDAC7 Protein, GST-tagged

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Cat.No. : HDAC7-4649H
Product Overview : Human HDAC7A full-length ORF ( AAH06453.1, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 56.1 kDa
AA Sequence : MGFCFFNSVA IACRQLQQQS KASKILIVDW DVHHGNGTQQ TFYQDPSVLY ISLHRHDDGN FFPGSGAVDE VGAGSGEGFN VNVAWAGGLD PPMGDPEYLA AFRIVVMPIA REFSPDLVLV SAGFDAAEGH PAPLGGYHVS AKCFGYMTQQ LMNLAGGAVV LALEGGHDLT AICDASEACV AALLGNRVDP LSEEGWKQKP NLNAIRSLEA VIRVHSKYWG CMQRLASCPD SWVPRVPGAD KEEVEAVTAL ASLSVGILAE DRPSEQLVEE EEPMNL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HDAC7 histone deacetylase 7 [ Homo sapiens ]
Official Symbol : HDAC7
Synonyms : HDAC7; histone deacetylase 7; HDAC7A, histone deacetylase 7A; DKFZP586J0917; HD7; histone deacetylase 7A; HD7A; HDAC7A; FLJ99588; DKFZp586J0917;
Gene ID : 51564
mRNA Refseq : NM_001098416
Protein Refseq : NP_001091886
MIM : 606542
UniProt ID : Q8WUI4

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