Recombinant Human HENMT1 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human HENMT1 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : HENMT1-210H
Product Overview : C1orf59 MS Standard C13 and N15-labeled recombinant protein (NP_653185) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 44.5 kDa
AA Sequence : MEENNLQCSS VVDGNFEEVP RETAIQFKPP LYRQRYQFVK NLVDQHEPKK VADLGCGDTS LLRLLKVNPC IELLVGVDIN EDKLRWRGDS LAPFLGDFLK PRDLNLTITL YHGSVVERDS RLLGFDLITC IELIEHLDSG DLARFPEVVF GYLSPSMIVI STPNSEFNPL FPSVTLRDSD HKFEWTRMEF QTWALYVANR YDYSVEFTGV GEPPAGAENV GYCTQIGIFR KNGGKATESC LSEQHDQHVY KAVFTTSYPS LQQERFFKLV LVNEVSQQVE SLRVSHLPRR KEQAGERGDK PKDIGGSKAP VPCFGPVFTE VEKAKIENSP TPFCVGDKFF VPLQRLLAYP KLNRLCANEE IMRSVIADSI PLSSDGSAVV ADLRNYFDEQ FEFTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis) [ Homo sapiens (human) ]
Official Symbol : HENMT1
Synonyms : HEN1; C1orf59; RP11-256E16.2
Gene ID : 113802
mRNA Refseq : NM_144584
Protein Refseq : NP_653185
MIM : 612178
UniProt ID : Q5T8I9

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