| Description : |
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
86.2 kDa |
| AA Sequence : |
MGRGSGTFERLLDKATSQLLLETDW ESILQICDLIRQGDTQAKYAVNSIK KKVNDKNPHVALYALEVMESVVKNC GQTVHDEVANKQTMEELKDLLKRQV EVNVRNKILYLIQAWAHAFRNEPKY KVVQDTYQIMKVEGHVFPEFKESDA MFAAERAPDWVDAEECHRCRVQFGV MTRKHHCRACGQIFCGKCSSKYSTI PKFGIEKEVRVCEPCYEQLNRKAEG KATSTTELPPEYLTSPLSQQSQLPP KRDETALQEEEELQLALALSQSEAE EKERLRQKSTYTSYPKAEPMPSASS APPASSLYSSPVNSSAPLAEDIDPE LARYLNRNYWEKKQEEARKSPTPSA PVPLTEPAAQPGEGHAAPTNVVENP LPETDSQPIPPSGGPFSEPQFHNGE SEESHEQFLKALQNAVTTFVNRMKS NHMRGRSITNDSAVLSLFQSINGMH PQLLELLNQLDERRLYYEGLQDKLA QIRDARGALSALREEHREKLRRAAE EAERQRQIQLAQKLEIMRQKKQEYL EVQRQLAIQRLQEQEKERQMRLEQQ KQTVQMRAQMPAFPLPYAQLQAMPA AGGVLYQPSGPASFPSTFSPAGSVE GSPMHGVYMSQPAPAAGPYPSMPST AADPSMVSAYMYPAGATGAQAAPQA QAGPTASPAYSSYQPTPTAGYQNVA SQAPQSLPAISQPPQSSTMGYMGSQ SVSMGYQPYNMQNLMTTLPSQDASL PPQQPYIAGQQPMYQQMAPSGGPPQ QQPPVAQQPQAQGPPAQGSEAQLIS FDTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
