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Recombinant Human HIF3A Protein, GST-tagged

Cat.No. : HIF3A-4749H
Product Overview : Human HIF3A full-length ORF ( AAH26308.1, 1 a.a. - 363 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 65.67 kDa
AA Sequence : MALGLQRARSTTELRKEKSRDAARS RRSQETEVLYQLAHTLPFARGVSAH LDKASIMRLTISYLRMHRLCAAGEW NQVGAGGEPLDACYLKALEGFVMVL TAEGDMAYLSENVSKHLGLSQLELI GHSIFDFIHPCDQEELQDALTPQQT LSRRKVEARTERCFSLRMKSTLTSR GRTLNLKAATWKVLNCSGHMRAYKP PAQTSPAGSPDSEPPLQCLVLICEA IPHPGSLEPPLGRGAFLSRHSLDMK FTYCDDRIAEVAGYSPDDLIGCSAY EYIHALDSDAVSKSIHTCMYPISPG AKPAATWPPADTRTPQLPIPQDALP PHLNTSSLLPKPQGTVSFLAPSYPV PRSFSPHLPPWWP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : HIF3A hypoxia inducible factor 3, alpha subunit [ Homo sapiens ]
Official Symbol : HIF3A
Synonyms : HIF3A; hypoxia inducible factor 3, alpha subunit; hypoxia-inducible factor 3-alpha; bHLHe17; IPAS; MOP7; PASD7; HIF3-alpha-1; member of PAS protein 7; inhibitory PAS domain protein; PAS domain-containing protein 7; basic-helix-loop-helix-PAS protein MOP7; class E basic helix-loop-helix protein 17; HIF-3A;
Gene ID : 64344
mRNA Refseq : NM_022462
Protein Refseq : NP_071907
MIM : 609976
UniProt ID : Q9Y2N7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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