Recombinant Human HIST1H2BB Protein (2-126 aa), His-SUMO-tagged

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Recombinant Human HIST1H2BB Protein (2-126 aa), His-SUMO-tagged

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Cat.No. : HIST1H2BB-553H
Product Overview : Recombinant Human HIST1H2BB Protein (2-126 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length of Mature Protein.
Description : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 29.8 kDa
Protein length : 2-126 aa
AA Sequence : PEPSKSAPAP KKGSKKAITK AQKKDGKKRK RSRKESYSIY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : HIST1H2BB histone cluster 1, H2bb [ Homo sapiens ]
Official Symbol : HIST1H2BB
Synonyms : HIST1H2BB; H2B/f; histone H2B.1; H2B.1; H2BFF; MGC119804;
Gene ID : 3018
mRNA Refseq : NM_021062
Protein Refseq : NP_066406
MIM : 602803
UniProt ID : P33778

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