Recombinant Human HLF, His-tagged

• Cat.No.: HLF-27715TH
• Product Overview: Recombinant full length Human HLF (amino acids 1-295 ) with a N terminal His tag. 315 amino acids with a predicted MWt 35.3 kDa including tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 295 amino acids
• Description: This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
• Conjugation: HIS
• Molecular Weight: 35.300kDa inclusive of tags
• Tissue specificity: Highly expressed in liver; lower levels in lung and kidney.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 1.17% Sodium chloride, 0.002% PMSF
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMEKMSRPLPLNPTFIPPPYG VLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPT VPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIP PSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHP GIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYE PDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKA RKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIA IRASFLEKENSALRQEVADLRKELGKCKNILAKYEARH GPL
• Sequence Similarities: Belongs to the bZIP family. PAR subfamily.Contains 1 bZIP domain.

Gene Information

• Gene Name: HLF hepatic leukemia factor [ Homo sapiens ]
• Official Symbol: HLF
• Synonyms: HLF; hepatic leukemia factor; MGC33822
• Gene ID: 3131
• mRNA Refseq: NM_002126
• Protein Refseq: NP_002117
• MIM: 142385
• Uniprot ID: Q16534
• Chromosome Location: 17q22
• Function: DNA binding; double-stranded DNA binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity