Recombinant Human HMG20A Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human HMG20A Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : HMG20A-6565H
Product Overview : HMG20A MS Standard C13 and N15-labeled recombinant protein (NP_060670) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 40.1 kDa
AA Sequence : MENLMTSSTL PPLFADEDGS KESNDLATTG LNHPEVPYSS GATSSTNNPE FVEDLSQGQL LQSESSNAAE GNEQRHEDEQ RSKRGGWSKG RKRKKPLRDS NAPKSPLTGY VRFMNERREQ LRAKRPEVPF PEITRMLGNE WSKLPPEEKQ RYLDEADRDK ERYMKELEQY QKTEAYKVFS RKTQDRQKGK SHRQDAARQA THDHEKETEV KERSVFDIPI FTEEFLNHSK AREAELRQLR KSNMEFEERN AALQKHVESM RTAVEKLEVD VIQERSRNTV LQQHLETLRQ VLTSSFASMP LPGSGETPTV DTIDSYMNRL HSIILANPQD NENFIATVRE VVNRLDRTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : HMG20A high mobility group 20A [ Homo sapiens (human) ]
Official Symbol : HMG20A
Synonyms : HMG20A; high mobility group 20A; high mobility group protein 20A; FLJ10739; HMG box domain containing 1; HMGX1; HMGXB1; high-mobility group 20A; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1;
Gene ID : 10363
mRNA Refseq : NM_018200
Protein Refseq : NP_060670
MIM : 605534
UniProt ID : Q9NP66

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