Recombinant Human HMGCLL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HMGCLL1-6528H
• Product Overview: HMGCLL1 MS Standard C13 and N15-labeled recombinant protein (NP_001035865) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: HMGCLL1 (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase Like 1) is a Protein Coding gene. Diseases associated with HMGCLL1 include 3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency and Breast Adenoid Cystic Carcinoma. Among its related pathways are Metabolism and Butanoate metabolism. Gene Ontology (GO) annotations related to this gene include lyase activity and hydroxymethylglutaryl-CoA lyase activity. An important paralog of this gene is HMGCL.
• Molecular Mass: 36.3 kDa
• AA Sequence: MGNVPSAVKHCLSYQQLLREHLWIGDSVAGALDPAQETSQLSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQMADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKVAQASFNATRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 [ Homo sapiens (human) ]
• Official Symbol: HMGCLL1
• Synonyms: HMGCLL1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1; ERCHL; er-cHL; bA418P12.1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1; endoplasmic reticulum 3-hydroxy-3-methylglutaryl-CoA lyase; endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase; probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; EC 4.1.3.4
• Gene ID: 54511
• mRNA Refseq: NM_001042406
• Protein Refseq: NP_001035865
• MIM: 619050
• UniProt ID: Q8TB92