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Recombinant Human HMGN3 protein, MYC/DDK-tagged

Cat.No.: HMGN3-524H
Product Overview: Recombinant Human HMGN3, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source: HEK293
Species: Human
Tag: MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 8.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: HMGN3 high mobility group nucleosomal binding domain 3 [ Homo sapiens ]
Official Symbol: HMGN3
Synonyms: HMGN3; high mobility group nucleosomal binding domain 3; thyroid hormone receptor interactor 7 , TRIP7; high mobility group nucleosome-binding domain-containing protein 3; TR-interacting protein 7; thyroid hormone receptor interacting protein 7; TRIP7; PNAS-24; PNAS-25; FLJ42187; DKFZp686E20226;
Gene ID: 9324
mRNA Refseq: NM_138730
Protein Refseq: NP_620058
MIM: 604502
UniProt ID: Q15651
Chromosome Location: 6q14.3
Function: DNA binding; chromatin binding; thyroid hormone receptor binding;

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