Recombinant Human HNRNPH3 Protein, GST-tagged

• Cat.No.: HNRNPH3-4904H
• Product Overview: Human HNRNPH3 full-length ORF ( NP_067676.2, 1 a.a. - 331 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61.6 kDa
• AA Sequence: MDWVMKHNGPNDASDGTVRLRGLPF GCSKEEIVQFFQGLEIVPNGITLTM DYQGRSTGEAFVQFASKEIAENALG KHKERIGHRYIEIFRSSRSEIKGFY DPPRRLLGQRPGPYDRPIGGRGGYY GAGRGSYGGFDDYGGYNNYGYGNDG FDDRMRDGRGMGGHGYGGAGDASSG FHGGHFVHMRGLPFRATENDIANFF SPLNPIRVHIDIGADGRATGEADVE FVTHEDAVAAMSKDKNNMQHRYIEL FLNSTPGGGSGMGGSGMGGYGRDGM DNQGGYGSVGRMGMGNNYSGGYGTP DGLGGYGRGGGGSGGYYGQGGMSGG GWRGMY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) [ Homo sapiens ]
• Official Symbol: HNRNPH3
• Synonyms: 2H9; HNRPH3
• Gene ID: 3189
• mRNA Refseq: NM_021644
• Protein Refseq: NP_067676
• MIM: 602324
• UniProt ID: P31942