Recombinant Human HNRPLL Protein, GST-tagged

• Cat.No.: HNRPLL-4919H
• Product Overview: Human HNRPLL full-length ORF (AAH17480.1, 1 a.a. - 542 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86.5 kDa
• AA Sequence: MSSSSSSPRETYEEDREYESQAKRL KTEEGEIDYSAEEGENRREATPRGG GDGGGGGRSFSQPEAGGSHHKVSVS PVVHVRGLCESVVEADLVEALEKFG TICYVMMMPFKRQALVEFENIDSAK ECVTFAADEPVYIAGQQAFFNYSTS KRITRPGNTDDPSGGNKVLLLSIQN PLYPITVDVLYTVCNPVGKVQRIVI FKRNGIQAMVEFESVLCAQKAKAAL NGADIYAGCCTLKIEYARPTRLNVI RNDNDSWDYTKPYLGRRDRGKGRQR QAILGEHPSSFRHDGYGSHGPLLPL PSRYRMGSRDTPELVAYPLPQASSS YMHGGNPSGSVVMVSGLHQLKMNCS RVFNLFCLYGNIEKVKFMKTIPGTA LVEMGDEYAVERAVTHLNNVKLFGK RLNVCVSKQHSVVPSQIFELEDGTS SYKDFAMSKNNRFTSAGQASKNIIQ PPSCVLHYYNVPLCVTEETFTKLCN DHEVLTFIKYKVFDAKPSAKTLSGL LEWECKTDAVEALTALNHYQIRVPN GSNPYTLKLCFSTSSHL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HNRPLL heterogeneous nuclear ribonucleoprotein L-like [ Homo sapiens ]
• Official Symbol: HNRPLL
• Synonyms: HNRPLL; heterogeneous nuclear ribonucleoprotein L-like; stromal RNA regulating factor; stromal RNA-regulating factor; SRRF; hnRNPLL
• Gene ID: 92906
• mRNA Refseq: NM_001142650
• Protein Refseq: NP_001136122
• MIM: 611208
• UniProt ID: Q8WVV9