Recombinant Human homer homolog 2 (Drosophila) Protein, His tagged

• Cat.No.: HOMER2-50H
• Product Overview: Recombinant human HOMER2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-343aa
• Description: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.
• Tag: N-His
• Form: Liquid
• Molecular Mass: 42.1 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMGSHMMGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
• Purity: > 85% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by Bradford assay)
• Storage Buffer: 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• References: 1. Brakeman P R., et al. (1997) Nature. 386:284-288.
  2. Tu J C., et al. (1998) Neuron. 21:717-726.

Gene Information

• Gene Name: HOMER2 homer homolog 2 (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: HOMER2
• Synonyms: HOMER2; homer homolog 2 (Drosophila); homer protein homolog 2; CPD; Cupidin; HOMER 2; HOMER 2A; HOMER 2B; Vesl 2; cupidin; homer homolog 3; homer, neuronal immediate early gene, 2; ACPD; VESL-2; HOMER-2
• Gene ID: 9455
• mRNA Refseq: NM_004839
• Protein Refseq: NP_004830
• MIM: 604799
• UniProt ID: Q9NSB8