Recombinant Human HPD Protein, His-tagged

• Cat.No.: HPD-01H
• Product Overview: Recombinant protein from the full-length sequence of homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), transcript variant 2 (NM_001171993), with a His tag was expressed in human cells.

Specification

• Description: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
• Source: Human Cells
• Species: Human
• Tag: His
• Molecular Mass: 47.1 kDa
• Endotoxin: < 0.1 ng/μg of protein (<1EU /μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Gene Information

• Gene Name: HPD 4-hydroxyphenylpyruvate dioxygenase [ Homo sapiens (human) ]
• Official Symbol: HPD
• Synonyms: HPD; 4-hydroxyphenylpyruvate dioxygenase; PPD; 4HPPD; GLOD3; 4-HPPD; HPPDASE; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; glyoxalase domain containing 3; EC 1.13.11.27
• Gene ID: 3242
• mRNA Refseq: NM_001171993
• Protein Refseq: NP_001165464
• MIM: 609695
• UniProt ID: P32754