Recombinant Human HPGD Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HPGD-5147H
• Product Overview: HPGD MS Standard C13 and N15-labeled recombinant protein (NP_000851) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29 kDa
• AA Sequence: MHVNGKVALVTGAAQGIGRAFAEAL LLKGAKVALVDWNLEAGVQCKAALD EQFEPQKTLFIQCDVADQQQLRDTF RKVVDHFGRLDILVNNAGVNNEKNW EKTLQINLVSVISGTYLGLDYMSKQ NGGEGGIIINMSSLAGLMPVAQQPV YCASKHGIVGFTRSAALAANLMNSG VRLNAICPGFVNTAILESIEKEENM GQYIEYKDHIKDMIKYYGILDPPLI ANGLITLIEDDALNGAIMKITTSKG IHFQDYDTTPFQAKTQTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HPGD 15-hydroxyprostaglandin dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: HPGD
• Synonyms: HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; SDR36C1; short chain dehydrogenase/reductase family 36C; member 1; prostaglandin dehydrogenase 1; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; short chain dehydrogenase/reductase family 36C, member 1; PGDH; PGDH1; PHOAR1; 15-PGDH
• Gene ID: 3248
• mRNA Refseq: NM_000860
• Protein Refseq: NP_000851
• MIM: 601688
• UniProt ID: P15428