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Recombinant Human HR Protein, GST-tagged

Cat.No. : HR-5022H
Product Overview : Human HR partial ORF ( NP_005135, 1090 a.a. - 1189 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR, cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : LDAGLRRRLREEWGVSCWTLLQAPG EAVLVPAGAPHQVQGLVSTVSVTQH FLSPETSALSAQLCHQGPSLPPDCH LLYAQMDWAVFQAVKVAVGTLQEAK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : HR hairless homolog (mouse) [ Homo sapiens ]
Official Symbol : HR
Synonyms : HR; hairless homolog (mouse); ALUNC, hairless (mouse) homolog; AU; ALUNC;
Gene ID : 3264
MIM : 602302
UniProt ID : O43593

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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