Recombinant Human HRAS (Q61L) Protein

• Cat.No.: HRAS-701H
• Product Overview: Recombinant Human HRAS protein (NP_005334，Q61L) was expressed in E. coli.

Specification

• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation Q61L results in a decreased GTPase activity as well as increased GDP/GTP exchange. This mutant constitutively activates the Ras-signaling pathway. Protein preparation is 77% GDP- and 23% GTP-loaded, measured by HPLC.
• Source: E. coli
• Species: Human
• Form: 64 mM Tris-HCl pH 7.2, 10 mM MgCl2 and 5 mM DTE
• Molecular Mass: 21.3 kDa
• Protein length: 189 amino acids
• Purity: > 95 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog [ Homo sapiens ]
• Official Symbol: HRAS
• Synonyms: CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1
• Gene ID: 3265
• mRNA Refseq: NM_005343.2
• Protein Refseq: NP_005334.1
• MIM: 190020
• UniProt ID: P01112