Recombinant Human HRH1 Protein, GST-tagged

• Cat.No.: HRH1-5034H
• Product Overview: Human HRH1 full-length ORF ( NP_000852.1, 1 a.a. - 487 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 82.2 kDa
• AA Sequence: MSLPNSSCLLEDKMCEGNKTTMASP QLMPLVVVLSTICLVTVGLNLLVLY AVRSERKLHTVGNLYIVSLSVADLI VGAVVMPMNILYLLMSKWSLGRPLC LFWLSMDYVASTASIFSVFILCIDR YRSVQQPLRYLKYRTKTRASATILG AWFLSFLWVIPILGWNHFMQQTSVR REDKCETDFYDVTWFKVMTAIINFY LPTLLMLWFYAKIYKAVRQHCQHRE LINRSLPSFSEIKLRPENPKGDAKK PGKESPWEVLKRKPKDAGGGSVLKS PSQTPKEMKSPVVFSQEDDREVDKL YCFPLDIVHMQAAAEGSSRDYVAVN RSHGQLKTDEQGLNTHGASEISEDQ MLGDSQSFSRTDSDTTTETAPGKGK LRSGSNTGLDYIKFTWKRLRSHSRQ YVSGLHMNRERKAAKQLGFIMAAFI LCWIPYFIFFMVIAFCKNCCNEHLH MFTIWLGYINSTLNPLIYPLCNENF KKTFKRILHIRS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HRH1 histamine receptor H1 [ Homo sapiens ]
• Official Symbol: HRH1
• Synonyms: HRH1; histamine receptor H1; histamine H1 receptor; H1R; HH1R; histamine H(1) receptor; histamine receptor, subclass H1; H1-R; hisH1
• Gene ID: 3269
• mRNA Refseq: NM_000861
• Protein Refseq: NP_000852
• MIM: 600167
• UniProt ID: P35367