Recombinant Human HSPA12A Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: HSPA12A-248H
• Product Overview: HSPA12A MS Standard C13 and N15-labeled recombinant protein (NP_079291) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 74.8 kDa
• AA Sequence: MADKEAGGSDGPRETAPTSAYSSPA RSLGDTGITPLSPSHIVNDTDSNVS EQQSFLVVVAVDFGTTSSGYAYSFT KEPECIHVMRRWEGGDPGVSNQKTP TTILLTPERKFHSFGYAARDFYHDL DPNEAKQWLYLEKFKMKLHTTGDLT MDTDLTAANGKKVKALEIFAYALQY FKEQALKELSDQAGSEFENSDVRWV ITVPAIWKQPAKQFMRQAAYQAGLA SPENSEQLIIALEPEAASIYCRKLR LHQMIELSSKAAVNGYSGSDTVGAG FTQAKEHIRRNRQSRTFLVENVIGE IWSELEEGDKYVVVDSGGGTVDLTV HQIRLPEGHLKELYKATGGPYGSLG VDYEFEKLLYKIFGEDFIEQFKIKR PAAWVDLMIAFESRKRAAAPDRTNP LNITLPFSFIDYYKKFRGHSVEHAL RKSNVDFVKWSSQGMLRMSPDAMNA LFKPTIDSIIEHLRDLFQKPEVSTV KFLFLVGGFAEAPLLQQAVQAAFGD QCRIIIPQDVGLTILKGAVLFGLDP AVIKVRRSPLTYGVGVLNRYVEGKH PPEKLLVKDGTRWCTDVFDKFISAD QSVALGELVKRSYTPAKPSQLVIVI NIYSSEHDNVSFITDPGVKKCGTLR LDLTGTSGTAVPARREIQTLMQFGD TEIKATAIDIATSKSVKVGIDFLNY TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HSPA12A heat shock 70kDa protein 12A [ Homo sapiens (human) ]
• Official Symbol: HSPA12A
• Synonyms: HSPA12A; heat shock 70kDa protein 12A; heat shock 70kD protein 12A; heat shock 70 kDa protein 12A; FLJ13874; KIAA0417
• Gene ID: 259217
• mRNA Refseq: NM_025015
• Protein Refseq: NP_079291
• MIM: 610701
• UniProt ID: O43301