Recombinant Human HSPH1 Protein, GST-tagged

• Cat.No.: HSPH1-5261H
• Product Overview: Human HSPH1 full-length ORF ( NP_006635.2, 1 a.a. - 858 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 123.3 kDa
• AA Sequence: MSVVGLDVGSQSCYIAVARAGGIET IANEFSDRCTPSVISFGSKNRTIGV AAKNQQITHANNTVSNFKRFHGRAF NDPFIQKEKENLSYDLVPLKNGGVG IKVMYMGEEHLFSVEQITAMLLTKL KETAENSLKKPVTDCVISVPSFFTD AERRSVLDAAQIVGLNCLRLMNDMT AVALNYGIYKQDLPSLDEKPRIVVF VDMGHSAFQVSACAFNKGKLKVLGT AFDPFLGGKNFDEKLVEHFCAEFKT KYKLDAKSKIRALLRLYQECEKLKK LMSSNSTDLPLNIECFMNDKDVSGK MNRSQFEELCAELLQKIEVPLYSLL EQTHLKVEDVSAVEIVGGATRIPAV KERIAKFFGKDISTTLNADEAVARG CALQCAILSPAFKVREFSVTDAVPF PISLIWNHDSEDTEGVHEVFSRNHA APFSKVLTFLRRGPFELEAFYSDPQ GVPYPEAKIGRFVVQNVSAQKDGEK SRVKVKVRVNTHGIFTISTASMVEK VPTEENEMSSEADMECLNQRPPENP DTDKNVQQDNSEAGTQPQVQTDAQQ TSQSPPSPELTSEENKIPDADKANE KKVDQPPEAKKPKIKVVNVELPIEA NLVWQLGKDLLNMYIETEGKMIMQD KLEKERNDAKNAVEEYVYEFRDKLC GPYEKFICEQDHQNFLRLLTETEDW LYEEGEDQAKQAYVDKLEELMKIGT PVKVRFQEAEERPKMFEELGQRLQH YAKIAADFRNKDEKYNHIDESEMKK VEKSVNEVMEWMNNVMNAQAKKSLD QDPVVRAQEIKTKIKELNNTCEPVV TQPKPKIESPKLERTPNGPNIDKKE EDLEDKNNFGAEPPHQNGECYPNEK NSVNMDLD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HSPH1 heat shock 105kDa/110kDa protein 1 [ Homo sapiens ]
• Official Symbol: HSPH1
• Synonyms: HSPH1; heat shock 105kDa/110kDa protein 1; heat shock protein 105 kDa; HSP105A; HSP105B; KIAA0201; NY CO 25; antigen NY-CO-25; heat shock 105kD beta; heat shock 105kD alpha; heat shock 110 kDa protein; heat shock 105kDa protein 1; HSP105; NY-CO-25; DKFZp686M05240
• Gene ID: 10808
• mRNA Refseq: NM_006644
• Protein Refseq: NP_006635
• MIM: 610703
• UniProt ID: Q92598