Recombinant Human HTRA1 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: HTRA1-090H
• Product Overview: HTRA1 MS Standard C13 and N15-labeled recombinant protein (NP_002766) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.53 kDa
• AA Sequence: MQIPRAALLPLLLLLLAAPASAQLS RAGRSAPLAAGCPDRCEPARCPPQP EHCEGGRARDACGCCEVCGAPEGAA CGLQEGPCGEGLQCVVPFGVPASAT VRRRAQAGLCVCASSEPVCGSDANT YANLCQLRAASRRSERLHRPPVIVL QRGACGQGQEDPNSLRHKYNFIADV VEKIAPAVVHIELFRKLPFSKREVP VASGSGFIVSEDGLIVTNAHVVTNK HRVKVELKNGATYEAKIKDVDEKAD IALIKIDHQGKLPVLLLGRSSELRP GEFVVAIGSPFSLQNTVTTGIVSTT QRGGKELGLRNSDMDYIQTDAIINY GNSGGPLVNLDGEVIGINTLKVTAG ISFAIPSDKIKKFLTESHDRQAKGK AITKKKYIGIRMMSLTSSKAKELKD RHRDFPDVISGAYIIEVIPDTPAEA GGLKENDVIISINGQSVVSANDVSD VIKRESTLNMVVRRGNEDIMITVIP EEIDPSGPSGPTRTRRLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HTRA1 HtrA serine peptidase 1 [ Homo sapiens (human) ]
• Official Symbol: HTRA1
• Synonyms: HTRA1; HtrA serine peptidase 1; ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11; serine protease HTRA1; IGFBP5-protease; high-temperature requirement A serine peptidase 1; protease, serine, 11 (IGF binding); EC 3.4.21.-
• Gene ID: 5654
• mRNA Refseq: NM_002775
• Protein Refseq: NP_002766
• MIM: 602194
• UniProt ID: Q92743