Recombinant Human IARS1 Protein (Met1-Arg500), N-His tagged

• Cat.No.: IARS1-3500H
• Product Overview: Recombinant human IARS1 (Met1-Arg500) protein fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1-Arg500
• Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.
• Molecular Mass: 60.44 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: IARS1 isoleucyl-tRNA synthetase 1 [ Homo sapiens (human) ]
• Official Symbol: IARS1
• Synonyms: IARS1; isoleucyl-tRNA synthetase 1; IRS; IARS; ILRS; ILERS; GRIDHH; PRO0785; isoleucine--tRNA ligase, cytoplasmic; isoleucine tRNA ligase 1, cytoplasmic; EC 6.1.1.5
• Gene ID: 3376
• mRNA Refseq: NM_013417
• Protein Refseq: NP_038203
• MIM: 600709
• UniProt ID: P41252