Recombinant Human ICOSLG protein, His-Avi-tagged

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Recombinant Human ICOSLG protein, His-Avi-tagged

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Cat.No. : ICOSLG-144H
Product Overview : Recombinant Human B7-H2 Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal. It contains Asp 19 - Ser 258.
Description : B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
Molecular Mass : The protein has a predicted MW of 29. 5 kDa. Due to glycosylation, the protein migrates to 55-70 KDa based on Bis-Tris PAGE result
Protein length : Asp19-Ser258
Endotoxin : Less than 0. 05 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : ICOSLG inducible T-cell co-stimulator ligand [ Homo sapiens ]
Official Symbol : ICOSLG
Synonyms : CD275 antigen; CD275; B7H2; B7-H2; B7H2B7 homolog 2; B7-H2B7-related protein 1; B7RP-1; B7RP1B7-like protein Gl50; B7RP-1LICOS; GL50; GL50transmembrane protein B7-H2 ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell co-stimulator ligand; KIAA0653ICOS ligand
Gene ID : 23308
mRNA Refseq : NM_001283050. 2
Protein Refseq : NP_001269979. 1
MIM : 605717
UniProt ID : O75144

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