Recombinant Human ID4, His-tagged

• Cat.No.: ID4-14045H
• Product Overview: Recombinant Human ID4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-70a.a.
• Description: This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein [ Homo sapiens ]
• Official Symbol: ID4
• Synonyms: ID4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-4; bHLHb27; class B basic helix-loop-helix protein 27; IDB4
• Gene ID: 3400
• mRNA Refseq: NM_001546
• Protein Refseq: NP_001537
• MIM: 600581
• UniProt ID: P47928
• Chromosome Location: 6p22.3
• Pathway: Id Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem
• Function: RNA polymerase II transcription factor binding; protein binding; transcription corepressor activity