"IDH2" Related Products

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Recombinant Human IDH2 Protein, His-tagged

Cat.No.: IDH2-994H
Product Overview: Recombinant human IDH2 protein, fused to His tag at N-terminus, was expressed in Insect cell.
Description: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
Source: Insect cells
Species: Human
Tag : His
Form: 50 mM Tris.HCl pH 8.0 , 150 mM NaCl, 10 % glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass: 46.6 kDa
Purity: >50 ug/mL as determined by microplate BCA method
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial [ Homo sapiens ]
Official Symbol: IDH2
Synonyms: D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH
Gene ID: 3418
mRNA Refseq: NM_002168
Protein Refseq: NP_002159
MIM: 147650
UniProt ID: P48735

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