Recombinant Human IDI2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IDI2-6350H
• Product Overview: IDI2 MS Standard C13 and N15-labeled recombinant protein (NP_150286) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.8 kDa
• AA Sequence: MSDINLDWVDRRQLQRLEEMLIVVD ENDKVIGADTKRNCHLNENIEKGLL HRAFSVVLFNTKNRILIQQRSDTKV TFPGYFTDSCSSHPLYNPAELEEKD AIGVRRAAQRRLQAELGIPGEQISP EDIVFMTIYHHKAKSDRIWGEHEIC YLLLVRKNVTLNPDPSETKSILYLS QEELWELLEREARGEVKVTPWLRTI AERFLYRWWPHLDDVTPFVELHKIH RVTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IDI2 isopentenyl-diphosphate delta isomerase 2 [ Homo sapiens (human) ]
• Official Symbol: IDI2
• Synonyms: IDI2; isopentenyl-diphosphate delta isomerase 2; isopentenyl-diphosphate Delta-isomerase 2; IPPI2; IPP isomerase 2; isopentenyl pyrophosphate isomerase 2; diphosphate dimethylallyl diphosphate isomerase 2
• Gene ID: 91734
• mRNA Refseq: NM_033261
• Protein Refseq: NP_150286
• MIM: 615389
• UniProt ID: Q9BXS1