Recombinant Full Length Human IDI2 Protein, C-Flag-tagged

• Cat.No.: IDI2-2165HFL
• Product Overview: Recombinant Full Length Human IDI2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 26.6 kDa
• AA Sequence: MSDINLDWVDRRQLQRLEEMLIVVD ENDKVIGADTKRNCHLNENIEKGLL HRAFSVVLFNTKNRILIQQR SDTKVTFPGYFTDSCSSHPLYNPAE LEEKDAIGVRRAAQRRLQAELGIPG EQISPEDIVFMTIYHHKAKS DRIWGEHEICYLLLVRKNVTLNPDP SETKSILYLSQEELWELLEREARGE VKVTPWLRTIAERFLYRWWP HLDDVTPFVELHKIHRV TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis

Gene Information

• Gene Name: IDI2 isopentenyl-diphosphate delta isomerase 2 [ Homo sapiens (human) ]
• Official Symbol: IDI2
• Synonyms: IPPI2
• Gene ID: 91734
• mRNA Refseq: NM_033261.3
• Protein Refseq: NP_150286.1
• MIM: 615389
• UniProt ID: Q9BXS1