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Active Recombinant Human IDO1 protein, His-tagged

Cat.No. : IDO1-008H
Product Overview : Active recombinant human N-terminal His-tagged IDO1 was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Source : E. coli
Species : Human
Tag : His
Form : 40 mM Tris-HCl, pH 8.0, with 110 mM sodium chloride, 2.2 mM potassium chloride, and 20% glycerol.
Bio-activity : IDO1 activity is measured by incubating with L-Trp substrate. After a three hour roomtemperature incubation, activity is determined by measuring the absorption of reaction product at λ = 320-325 nm.
Molecular Mass : 46 kDa
Protein length : 2-403 (full length)
Purity : ≥90% estimated by SDS-PAGE
Applications : Enzyme Activity
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US; may vary elsewhere
Gene Name : IDO1 indoleamine 2,3-dioxygenase 1 [ Homo sapiens (human) ]
Official Symbol : IDO1
Synonyms : Indoleamine 2,3-dioxygenase 1 Indoleamine-pyrrole 2,3-dioxygenase
Gene ID : 3620
mRNA Refseq : NM_002164
Protein Refseq : NP_002155
MIM : 147435
UniProt ID : P14902

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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08/12/2022

    The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

    05/14/2022

      Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

      03/12/2022

        The purchased proteins helped me to get satisfactory experimental results.

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