Recombinant Human IFNA7 Protein, His-tagged IFNA7-436H

Recombinant Human IFNA7 Protein, His-tagged

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Recombinant Human IFNA7 Protein, His-tagged

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Cat.No. : IFNA7-436H
Product Overview : Recombinant Human IFNA7 (NP_066401.2) (Cys24-Asp189) was expressed with a polyhistidine tag at the C-terminus.
Description : Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymph centigradeytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFN are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons.
Source : Yeast
Species : Human
Tag : His
Predicted N Terminal : Cys 24
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus. The ED50 for this effect is 3.0-15.0 pg/mL.
Molecular Mass : The recombinant human IFNA7 consists of 176 amino acids and predicts a molecular mass of 21 kDa
Protein length : Cys24-Asp189
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : IFNA7 interferon, alpha 7 [ Homo sapiens ]
Official Symbol : IFNA7
Synonyms : IFNA7; interferon, alpha 7; interferon alpha-7; IFN alphaJ; IFNA J; leIF J; IFN-alpha 7; IFN-alpha-7; IFN-alpha-J1; interferon alpha-J; interferon alpha-J1; IFNA-J; IFN-alphaJ;
Gene ID : 3444
mRNA Refseq : NM_021057
Protein Refseq : NP_066401
MIM : 147567
UniProt ID : P01567

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