| Species : |
Human |
| Source : |
Insect Cells |
| Tag : |
His |
| Protein Length : |
22-196 aa |
| Description : |
IFNL3, also known as Interferon lambda-3, is a secreted protein which belongs to the IL-28/IL-29 family. It is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. This protein displays potent antiviral activity and antitumor activity. It seems to signal through the Jak-STAT pathway. It also contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection. |
| Form : |
Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM EDTA, 0.1mM PMSF. |
| Molecular Mass : |
20.4kDa (181aa) 18-28kDa (SDS-PAGE under reducing conditions.) |
| AA Sequence : |
VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H |
| Endotoxin : |
< 1.0 eu per 1 microgram of protein (determined by lal |
| Purity : |
>85% by SDS - PAGE. |
| Storage : |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.25mg/ml (determined by Bradford assay) |
