Recombinant Human IGF1R protein, DDK-tagged
Cat.No. : | IGF1R-134H |
Product Overview : | Recombinant Human IGF1R(741-935aa) fused with DDK tag at C-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Source : | Insect cells |
Species : | Human |
Tag : | DDK |
Form : | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. |
Molecular Mass : | 22.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ] |
Official Symbol : | IGF1R |
Synonyms : | IGF1R; insulin-like growth factor 1 receptor; CD221; IGFIR; IGFR; JTK13; MGC18216; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor; MGC142170; MGC142172; |
Gene ID : | 3480 |
mRNA Refseq : | NM_000875 |
Protein Refseq : | NP_000866 |
MIM : | 147370 |
UniProt ID : | P08069 |
Chromosome Location : | 15q26.3 |
Pathway : | Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Apoptosis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; |
Function : | ATP binding; identical protein binding; insulin binding; insulin receptor binding; insulin receptor substrate binding; insulin-like growth factor I binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; nucleotide binding; phosphatidylinositol 3-kinase binding; protein binding; protein tyrosine kinase activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
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IGF1R-0996H | Recombinant Human IGF1R Protein (S982-K1286), Tag Free | +Inquiry |
IGF1R-2037R | Recombinant Rhesus Macaque IGF1R Protein, His (Fc)-Avi-tagged | +Inquiry |
IGF1R-0995H | Recombinant Human IGF1R Protein (S982-K1286), His tagged | +Inquiry |
IGF1R-1154H | Recombinant Human IGF1R Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IGF1R-2928HCL | Recombinant Human IGF1R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1600 | IGF1R Functional Assay Kit | +Inquiry |
Kit-1601 | HEK 293 IGF1R Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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