| Description : |
This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
C-His |
| Molecular Mass : |
The protein has a calculated MW of 110 kDa. |
| AA Sequence : |
MASAAVESFVTKQLDLLELERDAEV EERRSWQENISLKELQSRGVCLLKL QVSSQRTGLYGRLLVTFEPRRYGSA AALPSNSFTSGDIVGLYDAANEGSQ LATGILTRVTQKSVTVAFDESHDFQ LSLDRENSYRLLKLANDVTYRRLKK ALIALKKYHSGPASSLIEVLFGRSA PSPASEIHPLTFFNTCLDTSQKEAV LFALSQKELAIIHGPPGTGKTTTVV EIILQAVKQGLKVLCCAPSNIAVDN LVERLALCKQRILRLGHPARLLESI QQHSLDAVLARSDSAQIVADIRKDI DQVFVKNKKTQDKREKSNFRNEIKL LRKELKEREEAAMLESLTSANVVLA TNTGASADGPLKLLPESYFDVVVID ECAQALEASCWIPLLKARKCILAGD HKQLPPTTVSHKAALAGLSLSLMER LAEEYGARVVRTLTVQYRMHQAIMR WASDTMYLGQLTAHSSVARHLLRDL PGVAATEETGVPLLLVDTAGCGLFE LEEEDEQSKGNPGEVRLVSLHIQAL VDAGVPARDIAVVSPYNLQVDLLRQ SLVHRHPELEIKSVDGFQGREKEAV ILSFVRSNRKGEVGFLAEDRRINVA VTRARRHVAVICDSRTVNNHAFLKT LVEYFTQHGEVRTAFEYLDDIVPEN YSHENSQGSSHAATKPQGPATSTRT GSQRQEGGQEAAAPARQGRKKPAGK SLASEAPSQPSLNGGSPEGVESQDG VDHFRAMIVEFMASKKMQLEFPPSL NSHDRLRVHQIAEEHGLRHDSSGEG KRRFITVSKRAPRPRAALGPPAGTG GPAPLQPVPPTPAQTEQPPREQRGP DQPDLRTLHLERLQRVRSAQGQPAS KEQQASGQQKLPEKKKKKAKGHPAT DLPTEEDFEALVSAAVKADNTCGFA KCTAGVTTLGQFCQLCSRRYCLSHH LPEIHGCGERARAHARQRISREGVL YAGSGTKNGSLDPAKRAQLQRRLDK KLSELSNQRTSRRKERGTLEHHHHH H |
| Endotoxin : |
< 1 EU/μg by LAL |
| Purity : |
> 90% by SDS-PAGE |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : |
0.2 mg/mL by BCA |
| Storage Buffer : |
Sterile 50 mM Tris, pH7.5, 300 mM NaCl |
