Recombinant Human IKZF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human IKZF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : IKZF3-4296H
Product Overview : IKZF3 MS Standard C13 and N15-labeled recombinant protein (NP_036613) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 58 kDa
AA Sequence : MEDIQTNAEL KSTQEQSVPA ESAAVLNDYS LTKSHEMENV DSGEGPANED EDIGDDSMKV KDEYSERDEN VLKSEPMGNA EEPEIPYSYS REYNEYENIK LERHVVSFDS SRPTSGKMNC DVCGLSCISF NVLMVHKRSH TGERPFQCNQ CGASFTQKGN LLRHIKLHTG EKPFKCHLCN YACQRRDALT GHLRTHSVEK PYKCEFCGRS YKQRSSLEEH KERCRTFLQS TDPGDTASAE ARHIKAEMGS ERALVLDRLA SNVAKRKSSM PQKFIGEKRH CFDVNYNSSY MYEKESELIQ TRMMDQAINN AISYLGAEAL RPLVQTPPAP TSEMVPVISS MYPIALTRAE MSNGAPQELE KKSIHLPEKS VPSERGLSPN NSGHDSTDTD SNHEERQNHI YQQNHMVLSR ARNGMPLLKE VPRSYELLKP PPICPRDSVK VINKEGEVMD VYRCDHCRVL FLDYVMFTIH MGCHGFRDPF ECNMCGYRSH DRYEFSSHIA RGEHRALLKT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : IKZF3 IKAROS family zinc finger 3 [ Homo sapiens (human) ]
Official Symbol : IKZF3
Synonyms : IKZF3; IKAROS family zinc finger 3 (Aiolos); zinc finger protein, subfamily 1A, 3 (Aiolos), ZNFN1A3; zinc finger protein Aiolos; Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); AIO; AIOLOS; ZNFN1A3;
Gene ID : 22806
mRNA Refseq : NM_012481
Protein Refseq : NP_036613
MIM : 606221
UniProt ID : Q9UKT9

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