Recombinant Human IL10 protein, His-Avi-tagged

• Cat.No.: IL10-301H
• Product Overview: Recombinant human IL10 Protein is expressed from Expi293 with a His tag and Avi Tag at the N-terminal. It contains Ser19-Asn178.

Specification

• Description: Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in 20mM PBS,pH7.4.
• Molecular Mass: The protein has a predicted MW of 21.3 kDa.Due to glycosylation, the protein migrates to 23-25 KDa based on Bis-Tris PAGE result.
• Protein length: Ser19-Asn178
• Endotoxin: Less than 0.001 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL10
• Official Symbol: IL10
• Synonyms: Interleukin-10, IL-10, CSIF
• Gene ID: 3586
• mRNA Refseq: NM_000572.2
• Protein Refseq: NP_000563.1
• MIM: 124092
• UniProt ID: P22301