"IL12A" Related Products

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Recombinant Human IL12A protein, His & S-tagged

Cat.No. : IL12A-850H
Product Overview : Recombinant Human IL12A aa. (Arg23~Ser219 (Accession # P29459)) fused with N-terminal His & S tag was produced in E. coli cells.
Description : This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Source : E. coli
Species : Human
Tag : His & S
Form : Freeze-dried powder
Molecular Mass : 33kDa as determined by SDS-PAGE reducing conditions
Protein length : Arg23~Ser219 (Accession # P29459)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative
Reconstitution : Reconstitute in ddH2O.
SDS-PAGE :

Gene Name : IL12A interleukin 12A [ Homo sapiens (human) ]
Official Symbol : IL12A
Synonyms : IL12A; interleukin 12A; P35; CLMF; NFSK; NKSF1; IL-12A; interleukin-12 subunit alpha; CLMF p35; IL-12, subunit p35; IL35 subunit; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12, p35; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 alpha chain
Gene ID : 3592
mRNA Refseq : NM_000882.3
Protein Refseq : NP_000873.2
UniProt ID : P29459

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