Recombinant Human IL17D protein

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Recombinant Human IL17D protein

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Cat.No. : IL17D-128H
Product Overview : Recombinant Human IL17D was expressed in E. coli.
Description : Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.
Source : E. coli
Species : Human
Form : Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)
Bio-activity : The ED50 is 7.5-37.5 ng/mL as determined by its binding ability in a functional ELISA (at a concentration of 1 μg/mL).
Molecular Mass : 20.5 kDa
Endotoxin : <1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity : >95%
Applications : Cell Assay
Storage : The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade - 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Reconstitution : Reconstitute in sterile 4mM HCl at 100μg/mL (containing at least 0.1% human or bovine serum albumin)
Figure :

Gene Name : IL17D interleukin 17D [ Homo sapiens ]
Official Symbol : IL17D
Synonyms : IL17D; interleukin 17D; interleukin-17D; FLJ30846; IL 17D; IL 22; IL 27; IL27; interleukin 27; interleukin-27; IL-22; IL-27; IL-17D;
Gene ID : 53342
mRNA Refseq : NM_138284
Protein Refseq : NP_612141
MIM : 607587
UniProt ID : Q8TAD2
Chromosome Location : 13q11
Function : cytokine activity;

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