Active Recombinant Human IL17RB Protein, hIgG/His-tagged
Cat.No. : | IL17RB-01H |
Product Overview : | Recombinant human IL-17RB (18-292aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. |
Source : | Insect cell |
Species : | Human |
Tag : | hIgG/His |
Form : | Liquid |
Bio-activity : | Measured by its binding ability in a functional ELISA with Human IL25. The ED50 range ≤ 2 μg/mL. |
Molecular Mass : | 57.3 kDa (514aa), reducing conditions |
AA Sequence : | REPTVQCGSETGPSPEWMLQHDLIP GDLRDLRVEPVTTSVATGDYSILMN VSWVLRADASIRLLKATKICVTGKS NFQSYSCVRCNYTEAFQTQTRPSGG KWTFSYIGFPVELNTVYFIGAHNIP NANMNEDGPSMSVNFTSPGCLDHIM KYKKKCVKAGSLWDPNITACKKNEE TVEVNFTTTPLGNRYMALIQHSTII GFSQVFEPHQKKQTRASVVIPVTGD SEGATVQLTPYFPTCGSDCIRHKGT VVLCPQTGVPFPLDNNKSKPGGWLP |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 85% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/mL (determined by Bradford assay) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | IL17RB interleukin 17 receptor B [ Homo sapiens (human) ] |
Official Symbol : | IL17RB |
Synonyms : | IL17RB; interleukin 17 receptor B; CRL4; EVI27; IL17BR; IL17RH1; interleukin-17 receptor B; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17RB; IL-17Rh1; cytokine receptor CRL4; cytokine receptor-like 4; interleukin 17 receptor homolog 1; interleukin-17B receptor |
Gene ID : | 55540 |
mRNA Refseq : | NM_018725 |
Protein Refseq : | NP_061195 |
MIM : | 605458 |
UniProt ID : | Q9NRM6 |
Products Types
◆ Recombinant Protein | ||
IL17RB-3369M | Active Recombinant Mouse IL17RB protein(Met1-Gly286), His-tagged | +Inquiry |
IL17RB-2295H | Recombinant Human IL17RB Protein, His-tagged | +Inquiry |
IL17RB-990R | Recombinant Rhesus IL17RB Protein (Met1-Gly288), HlgG1 Fc-tagged | +Inquiry |
IL17RB-96H | Recombinant Human IL17RB Protein, His (Fc)-Avi-tagged | +Inquiry |
IL17RB-7987H | Recombinant Human IL17RB protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
IL17RB-871HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-549HCL | Recombinant Human IL17RB cell lysate | +Inquiry |
IL17RB-1115MCL | Recombinant Mouse IL17RB cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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