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Recombinant Human IL1RAP Protein, hFc-tagged, Alexa Fluor 488 conjugated
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March 30, 2023 | Add to Quote |
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Cat.No. : | IL1RAP-627HAF488 Optional Service: Optional requirements on this protein |
Product Overview : | Alexa Fluor 488 conjugated recombinant human IL1RAP (Ser21-Glu359) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
Description : | Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3/IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. |
Source : | HEK293 |
Species : | Human |
Tag : | hFc |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 65.7 kDa. The protein migrates as 75-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ser21-Glu359 |
N-terminal Sequence Analysis : | Ser 21 |
Endotoxin : | < 1.0 EU/ μg by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 488 via amines Excitation Wavelength: 488 nm Emission Wavelength: 515-545 nm |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | IL1RAP |
Official Symbol : | IL1RAP |
Synonyms : | IL1RAP; interleukin 1 receptor accessory protein; interleukin-1 receptor accessory protein; C3orf13; IL 1RAcP; IL1R3; IL-1R3; interleukin-1 receptor 3; IL-1 receptor accessory protein; interleukin-1 receptor accessory protein beta; IL-1RAcP; FLJ37788 |
Gene ID : | 3556 |
mRNA Refseq : | NM_001167928 |
Protein Refseq : | NP_001161400 |
MIM : | 602626 |
UniProt ID : | Q9NPH3 |
◆ Recombinant Protein
IL1RAP-356H | Recombinant Human IL1RAP Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Il1rap-443M | Recombinant Mouse IL1RAP Protein, His-tagged | +Inquiry |
Il1rap-3508M | Recombinant Mouse Il1rap Protein, Myc/DDK-tagged | +Inquiry |
Il1rap-444M | Recombinant Mouse IL1RAP Protein, Fc-tagged | +Inquiry |
IL1RAP-1820H | Recombinant Human IL1RAP Protein, MYC/DDK-tagged | +Inquiry |
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◆ Lysates
IL1RAP-2730HCL | Recombinant Human IL1RAP cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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