IL1RAP-093HB
Optional Service: Optional requirements on this protein
Product Overview :
Biotinylated Recombinant Human IL-1R3 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Ser21-Glu359.
Description :
IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Source :
HEK293
Species :
Human
Tag :
His-Avi
Form :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Molecular Mass :
The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Bis-Tris PAGE result.
Protein length :
Ser21-Glu359
Endotoxin :
Less than 1 EU per μg by the LAL method.
Purity :
>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Storage :
The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.